脂溢性皮炎

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Cell得了过敏性皮炎为何发痒关键词过敏 [复制链接]

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Highlights

Heterogeneousformsofitchunderlieatopicdermatitis

Basophilspromoteamastcell-independentformofIgE-mediateditch

Allergen-stimulatedbasophilsreleaseleukotrieneC4andinteractwithsensorynerves

LeukotrieneC4-CysLTR2neuronalsignalingmediatesacuteitchflares

Summary

Itchisanevolutionarilyconservedsensationthatfacilitatesexpulsionofpathogensandnoxiousstimulifromtheskin.However,inorganfailure,cancer,andchronicinflammatorydisorderssuchasatopicdermatitis(AD),itchbe

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